Organic chemistry: Is the planet shaking or is it just me ?

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In 1820, caffeine was first isolated from coffee by the German chemist Friedlieb Ferdinand Runge, apparently at the behest of Johan Wolfgang von Goethe. The following year, the French chemist Pierre Joseph Pelletier, coined the word ‘cafeine’ after the French derivation for the word coffee; café. However, it was not until the end of the 19th century that its complete chemical structure was discovered by Hermann Ermil Fischer, who was the first person to achieve its total synthesis. Fishcher was later awarded the Nobel Prize in 1902 for his work in this field of organic chemistry.

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